successful treatment of multiorgan toxicity induced by explosive agent with repeated hemodialysis: a case report

نویسندگان

mohammad arefi department of clinical toxicology, school of medicine, baharloo hospital, tehran university of medical sciences, tehran, ir iran

hamidreza mohammadi department of clinical toxicology, school of medicine, baharloo hospital, tehran university of medical sciences, tehran, ir iran; pharmacutical science research center, mazandaran university of medical sciences, sari, ir iran; department of toxicology and pharmacology, faculty of pharmacy, mazandaran university of medical sciences, sari, ir iran; department of toxicology and pharmacology, faculty of pharmacy, mazandaran university of medical sciences, sari, ir iran. tel: +98-1513543082, fax: +98-1513543085

چکیده

introduction acute poisoning by oral ingestion of mixed hazardous materials can lead to multiorgan toxicity and may represent a special challenge in clinical management, in particular if little is known about the effects of the involved agents. this is especially true when industrial chemical substances have been swallowed, as a huge variety of toxic substances must be taken into account. conclusions in cases of oral-based multiple hazardous substance toxicity without a specific antidote, hemodialysis seems to be the best treatment. the problems created by multiorgan toxicity and the issues involved in the decision-making process are discussed in the management of this extraordinarily overwhelming complication. case presentation this case report describes the management of this potentially life-threatening situation in a 21-year-old man with multiorgan system failure, who developed gastrointestinal bleeding, anemia, renal dysfunction, altered visual acuity, seizure, jaundice, and ascites due to multiorgan toxicity. this patient was successfully treated with repeated hemodialysis, and survived. he was discharged from the hospital with an acceptable level of morbidity.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Case Report of Successful Treatment of Aluminum Phosphide Poisoning

Introduction: Aluminum phosphide is one of the most common causes of poisoning in the country. It liberates lethal phosphine gas when it comes in contact either with atmospheric moisture or with hydrochloric acid in the stomach. It mainly attacks the cardiovascular and respiratory systems. Eating even small amounts of this toxin can lead to death. This study reports a case of successful treatme...

متن کامل

Successful Treatment of Aluminium Phosphide Poisoning: A Case Report

Aluminium phosphide (AlP) is used to kill rodents in grain storage. It produces phosphine gas which is toxic for mitochondria. The exact mechanism of action is unclear, but phosphine is thought to produce toxicity by blocking cytochrome-c oxidase, which inhibits oxidative phosphorylation and result in cell death. This poisoning has a high mortality, and survival is unlikely if more than 1.5 g i...

متن کامل

Successful Treatment of Refractory Thrombotic Thrombocytopenic Purpura with Rituximab, a Monoclonal Antibody: a Case Report

Thrombotic thrombocytopenic purpura (TTP) is mostly attributed to the presence of an autoantibody against ADAMTS-13, a metalloprotease that degrades ultralarge von Willebrand protein multimers. Accumulation of vWF multimers and systemic platelet aggregation lead to microangiopathic thrombosis, hemolytic anemia, and end-organ ischemia. Most patients respond to therapeutic plasma exchange (TPE), ...

متن کامل

Successful treatment of inflammatory myofibroblastic tumor by surgical resection and radiotherapy: A case report

Background: Inflammatory myofibroblastic tumor (IMT) is a tumor composed of myofibroblasts and a mixed inflammatory infiltrate that rarely undergoes malignant transformation. The most common sites of involvement include the lung, liver and orbit, but it has been reported to occur in nearly every site of the body, including oral cavity and soft tissue. Although common in other sites, such a tumo...

متن کامل

Multiorgan Hydatid Cyst: A Case Report

  Hydatid disease is endemic in some parts of the world. This disease can occur in any organ. We present a 22-year-old farmer who was suffering from hydatidosis for 4 years. He was admitted to the hospital because of fever, cough, and chest pain in 2004. A chest radiograph revealed multiple nodules in both of lungs. A transthoracic echocardiogram showed cystic lesion in the apex of right ventr...

متن کامل

Successful treatment of nephrotic syndrome in twin pregnancy: case report

Background: Nephrotic syndrome is a kidney disorder that is identified by signs of nephrosis, severe proteinuria, hypoalbuminemia, and edema. It is a component of glomerulonephrosis, in which different degrees of proteinuria may occur. The complications of this syndrome may include blood clots, infections, and high blood pressure. Essentially, decreased protein through the kidneys (proteinuria)...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
jundishapur journal of natural pharmaceutical products

جلد ۱۱، شماره ۴، صفحات ۰-۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023